Potentiometric pKa determination of water-insoluble compounds: validation study in methanol/water mixtures
International Journal of Pharmaceutics, Volume 151, Issue 2, 26 May 1997, Pages 235-248
Krisztina Takács-Novák, Karl J. Box and Alex Avdeef
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http://dx.doi.org/10.1016/S0378-5173(97)04907-7