Design, synthesis, structure–activity relationship, and in vivo activity of azabicyclic aryl amides as α7 nicotinic acetylcholine receptor agonists
Daniel P. Walkera, Donn G. Wishkaa, David W. Piotrowskia, Shaojuan Jia†, a, Steven C. Reitza, Karen M. Yatesa, Jason K. Myers†, a, Tatiana N. Vetman†, a, Brandon J. Margolis†, a, E. Jon Jacobsena, Brad A. Ackera, Vincent E. Groppia, Mark L. Wolfe‡, a, Bruce A. Thornburgha, Paula M. Tinholta, Luz A. Cortes-Burgosa, Rodney R. Waltersa, Matthew R. Hestera, Eric P. Seest†, a, Lester A. Dolaka, Fusen Han§, a, Barbara A. Olsona, Laura Fitzgeralda, Brian A. Staton†, a, Thomas J. Raub†, a, Mihaly Hajosa, William E. Hoffmanna, Kai S. Lia, Nicole R. Higdon‡, a, Theron M. Wall‡, a, Raymond S. Hursta, Erik H.F.
Bioorganic & Medicinal Chemistry
Volume 14, Issue 24, 15 December 2006, Pages 8219-8248
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http://dx.doi.org/10.1016/j.bmc.2006.09.019 