Discovery of 4-{4-[3-(Pyridin-2-yl)-1H-pyrazol-4-yl]pyridin-2-yl}-N-(tetrahydro-2H- pyran-4-yl)benzamide (GW788388): A Potent, Selective, and Orally Active Transforming Growth Factor-β Type I Receptor Inhibitor
Françoise Gellibert,*† Anne-Charlotte de Gouville,‡ James Woolven,§ Neil Mathews, Van-Loc Nguyen,† Cécile Bertho-Ruault,† Angela Patikis, Eugene T. Grygielko, Nicholas J. Laping, and Stéphane Huet‡
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http://dx.doi.org/10.1021/jm0509905