1) Nonquaternary cholinesterase reactivators. 3. 3(5)-Substituted 1,2,4-oxadiazol-5(3)-aldoximes and 1,2,4-oxadiazole-5(3)-thiocarbohydroximates as reactivators of organophosphonate-inhibited eel and human acetylcholinesterase in vitro.
Clifford D. Bedford, Robert A. Howd, Oliver D. Dailey, Alexi Miller, Harold W. Nolen III, Richard A. Kenley, John R. Kern, John S. Winterle
J. Med. Chem., 1986, 29 (11), pp 2174–2183
Код: Выделить всё
http://dx.doi.org/10.1021/jm00161a0082) Synthesis of (R) and (S) enantiomers of Fmoc-protected 1,2,4-oxadiazole-containing β3-amino acids from Fmoc-(R)-β-HAsp(OtBu)-OH
Abdallah Hamzéa, Jean-François Hernandez, a, and Jean Martineza
Tetrahedron Letters, Volume 44, Issue 32, 4 August 2003, Pages 6079-6082
Код: Выделить всё
http://dx.doi.org/10.1016/S0040-4039(03)01471-03) Muscarinic acetylcholine receptor antagonists: SAR and optimization of tyrosine ureas
Jian Jin, Yonghui Wang, et al.
Bioorganic & Medicinal Chemistry Letters, Volume 18, Issue 20, 15 October 2008, Pages 5481-5486
Код: Выделить всё
http://dx.doi.org/10.1016/j.bmcl.2008.09.0204) Discovery of the First Potent and Orally Efficacious Agonist of the Orphan G-Protein Coupled Receptor 119
Graeme Semple et al.
J. Med. Chem., 2008, 51 (17), pp 5172–5175
Код: Выделить всё
http://dx.doi.org/10.1021/jm8006867