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1. Quinazoline antifolate thymidylate synthase inhibitors: difluoro-substituted benzene ring analogs
Timothy J. Thornton, Ann L. Jackman, Peter R. Marsham, Brigid M. O'Connor, Joel A. M. Bishop, A. Hilary Calvert
J. Med. Chem., 1992, 35 (12), pp 2321–2327
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http://dx.doi.org/10.1021/jm00090a024Jung-Mo Ahn, a, and Sun-Young Hana
Tetrahedron Letters, Vol. 48, Issue 20, 14 May 2007, Pages 3543-3547
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http://dx.doi.org/10.1016/j.tetlet.2007.03.108