+++7 статей ACS (ACS Med. Chem. Lett)

[ursus2010]

Уважаемые коллеги!

Помогите, пожалуйста, со статьями:

1) "Discovery of a Potent, Injectable Inhibitor of Aurora Kinases Based on the Imidazo-[1,2-a]-Pyrazine Core"
Tao Yu†, Jayaram R. Tagat
ACS Med. Chem. Lett., ACS Medicinal Chemistry Letters, , , pp –

DOI:

http://dx.doi.org/10.1021/ml100063w

2) Quinolizidinone Carboxylic Acids as CNS Penetrant, Selective M1 Allosteric Muscarinic Receptor Modulators
Scott D. Kuduk, Ronald K. Chang, Christina N. Di Marco, William J. Ray, Lei Ma, Marion Wittmann, Matthew A. Seager, Kenneth A. Koeplinger, Charles D. Thompson, George D. Hartman and Mark T. Bilodeau
ACS Med. Chem. Lett., ACS Medicinal Chemistry Letters, , , pp –

DOI:

http://dx.doi.org/10.1021/ml100095k

3)
The Discovery of Pyridone and Pyridazone Heterocycles as γ-Secretase Modulators
Xianhai Huang, Robert Aslanian, Wei Zhou, Xiaohong Zhu, Jun Qin, William Greenlee, Zhaoning Zhu, Lili Zhang, Lynn Hyde, Inhou Chu, Mary Cohen-Williams and Anandan Palani
ACS Med. Chem. Lett., ACS Medicinal Chemistry Letters, , , pp –

DOI:

http://dx.doi.org/10.1021/ml1000799

4) Discovery of Dinaciclib (SCH 727965): A Potent and Selective Inhibitor of Cyclin-Dependent Kinases
Kamil Paruch, Michael P. Dwyer
ACS Med. Chem. Lett., ACS Medicinal Chemistry Letters, , , pp –

DOI:

http://dx.doi.org/10.1021/ml100051d

5)
Discovery of Potent and Selective Urea-Based ROCK Inhibitors and Their Effects on Intraocular Pressure in Rats
Yan Yin, Michael D. Cameron
ACS Med. Chem. Lett., ACS Medicinal Chemistry Letters, , , pp –

DOI:

http://dx.doi.org/10.1021/ml1000382

6) Strategic Use of Plasma and Microsome Binding To Exploit in Vitro Clearance in Early Drug Discovery
George Chang
ACS Med. Chem. Lett., 2010, 1 (2), pp 50–53

DOI:

http://dx.doi.org/10.1021/ml900012h

7) Synthesis and In Vitro Evaluation of Imidazo[1,2-b]pyridazines as Ligands for β-Amyloid Plaques
Fanxing Zeng
ACS Med. Chem. Lett., 2010, 1 (2), pp 80–84

DOI:

http://dx.doi.org/10.1021/ml100005j

Заранее большое спасибо!!

[bromin]