+++Org. Process Res. Dev

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+++Org. Process Res. Dev

Сообщение Liverpool » Ср июл 07, 2010 4:38 pm

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1) Concise Synthesis of C2-Symmetrical 2,6-Disubstituted Morpholines by N → O Boc Migration under SL-PTC Conditions
Domenico Albanese, Dario Landini, Michele Penso, Aaron Tagliabue and Emanuele Carlini
Org. Process Res. Dev. 2010, 14 (3), pp 705–711

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http://dx.doi.org/10.1021/op1000435
2) Aminolysis of Epoxides in a Microreactor System: A Continuous Flow Approach to β-Amino Alcohols
Matthew W. Bedore, Nikolay Zaborenko, Klavs F. Jensen and Timothy F. Jamison
Org. Process Res. Dev. 2010, 14 (2), pp 432–440

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http://dx.doi.org/10.1021/op9003136
3) Removal of Heavy Metals from Organic Reaction Mixtures: Preparation and Application of Functionalized Resins
Damien Barbaras, Jrg Brozio, Ib Johannsen and Thomas Allmendinger
Org. Process Res. Dev. 2009, 13 (6), pp 1068–1079

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http://dx.doi.org/10.1021/op900102a
4) Preparation of Saxagliptin, a Novel DPP-IV Inhibitor
Scott A. Savage, Gregory S. Jones, Sergei Kolotuchin, Shelly Ann Ramrattan, Truc Vu and Robert E. Waltermire
Org. Process Res. Dev. 2009, 13 (6), pp 1169–1176

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http://dx.doi.org/10.1021/op900226j
5) Practical Diastereoselective Synthesis and Scale-up Study of (+)-2-((1R,2R,3R,5S)-2-Amino-6,6-dimethylbicyclo[3.1.1]hept-3-yl)ethanol: A Key Intermediate of the Novel Prostaglandin D2 Receptor Antagonist S-5751
Takemasa Hida, Susumu Mitsumori, Tsunetoshi Honma, Yoshiharu Hiramatsu, Hiroshi Hashizume, Tetsuo Okada, Makoto Kakinuma, Kyozo Kawata, Katsuo Oda, Aiko Hasegawa, Toshiaki Masui and Hideo Nogusa
Org. Process Res. Dev. 2009, 13 (6), pp 1413–1418

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http://dx.doi.org/10.1021/op9001092
6) Aqueous Process Chemistry: The Preparation of Aryl Sulfonyl Chlorides
Philip J. Hogan and Brian G. Cox
Org. Process Res. Dev. 2009, 13 (5), pp 875–879

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http://dx.doi.org/10.1021/op9000862
7) Large-Scale Synthesis of a Selective Inhibitor of the Norepinephrine Transporter: Mechanistic Aspects of Conversion of Indolinone Diol to Indolinone Aminoalcohol and Process Implications
Asaf Alimardanov, Alexander Gontcharov, Antonia Nikitenko, Anita W. Chan, Zhixian Ding, Mousumi Ghosh, Mahmut Levent, Panolil Raveendranath, Jianxin Ren, Maotang Zhou, Paige E. Mahaney, Casey C. McComas, Joseph Ashcroft and John R. Potoski
Org. Process Res. Dev. 2009, 13 (5), pp 880–887

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http://dx.doi.org/10.1021/op900141r
8 ) Online Analysis of Flowing Streams Using Microflow HPLC
Christopher J. Welch, Xiaoyi Gong, James Cuff, Sarah Dolman, Jason Nyrop, Fiona Lin and Hallena Rogers
Org. Process Res. Dev. 2009, 13 (5), pp 1022–1025

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http://dx.doi.org/10.1021/op9001017
9) Development of a Practical Synthesis of an Aminoindanol-Derived M1 Agonist
Marvin M. Hansen, Sandra S. K. Borders, Marcella T. Clayton, Perry C. Heath, Stanley P. Kolis, Samuel D. Larsen, Ryan J. Linder, Susan M. Reutzel-Edens, Justin C. Smith, Shella L. Tameze, Jeffrey A. Ward and Leland O. Weigel
Org. Process Res. Dev. 2009, 13 (2), pp 198–208

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http://dx.doi.org/10.1021/op800243q
10) A Convergent Process for the Preparation of Adamantane 11-β-HSD-1 Inhibitors
Calvin L. Becker, Kenneth M. Engstrom, Francis A. Kerdesky, John C. Tolle, Seble H. Wagaw and Weifeng Wang
Org. Process Res. Dev. 2008, 12 (6), pp 1114–1118

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http://dx.doi.org/10.1021/op800065q
11) A Practical Synthesis of a Chiral Analogue of FTY720
Xinglong Jiang, Baoqing Gong, Kapa Prasad and Oljan Repi
Org. Process Res. Dev. 2008, 12 (6), pp 1164–1169

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http://dx.doi.org/10.1021/op800144h
12) Development of a Synthesis For a Long-Term Oxazolidinone Antibacterial
Allison Choy, Norman Colbry, Christian Huber, Michael Pamment and Justin Van Duine
Org. Process Res. Dev. 2008, 12 (5), pp 884–887

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http://dx.doi.org/10.1021/op8001195
13) A Novel, Safe, and Robust Nitration Process for the Synthesis of 4-(4-Methoxy-3-nitrophenyl)morpholine
Pingsheng Zhang, Ashish Shankar, Thomas P. Cleary, Miall Cedilote, Dobbert Locklear and Michael E. Pierce
Org. Process Res. Dev. 2007, 11 (5), pp 861–864

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http://dx.doi.org/10.1021/op700074k
14) New Synthetic Approach to Memantine Hydrochloride starting from 1,3-Dimethyl-adamantane
Mukesh K. Madhra, Mukesh Sharma and C. H. Khanduri
Org. Process Res. Dev. 2007, 11 (5), pp 922–923

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http://dx.doi.org/10.1021/op700138p
15) Scale-Up of the Preparation of (1R,2R,4S)-1-Methyl-4-(1-methylethenyl)-2-(4-morpholinyl)cyclohexanol
Christian T. Goralski, Dennis L. Hasha, Bakthan Singaram, and Derek Steiner
Org. Process Res. Dev. 2007, 11 (4), pp 776–779

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http://dx.doi.org/10.1021/op700092n
16) Process Development and Scale-up for (±)-Reboxetine Mesylate
Kevin E. Henegar, Cynthia T. Ball, Carolyn M. Horvath, Keith D. Maisto, and Sarah E. Mancini
Org. Process Res. Dev. 2007, 11 (3), pp 346–353

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http://dx.doi.org/10.1021/op7000063
17) Process Development for (S,S)-Reboxetine Succinate via a Sharpless Asymmetric Epoxidation
Kevin E. Henegar and Mateusz Cebula
Org. Process Res. Dev. 2007, 11 (3), pp 354–358

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http://dx.doi.org/10.1021/op700007g
18 ) An Alternative Approach to Achieve Enantiopure (3S)-4-Benzyl-3- (4-fluorophenyl)morpholin-2-one: A Key Intermediate of Aprepitant, an NK1 Receptor Antagonist
Naveenkumar Kolla, Chandrashekar R. Elati, Muthulingam Arunagiri, Srinivas Gangula, Pravinchandra J. Vankawala, Yerremilli Anjaneyulu, Apurba Bhattacharya, Sundaram Venkatraman, and Vijayavitthal T. Mathad
Org. Process Res. Dev. 2007, 11 (3), pp 455–457

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http://dx.doi.org/10.1021/op700030d
19) An Improved Process for the Preparation of 4,4-Dimethyloxazolidine-2-thione
Neera Tewari, Dinesh Nair, Hashim Nizar, Bishwa Prakash Rai, and Mohan Prasad
Org. Process Res. Dev. 2007, 11 (3),pp 466–467

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http://dx.doi.org/10.1021/op6002677
20) An Improved Synthesis of Memantine Hydrochloride: Anti-Alzheimer's Drug
Jambula Mukunda Reddy, Ganji Prasad, Veeramalla Raju, Mylavarapu Ravikumar, Vurumidi Himabindu, and Ghanta Mahesh Reddy
Org. Process Res. Dev. 2007, 11 (2),pp 268–269

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http://dx.doi.org/10.1021/op060246+
21) Epoxidation of Allyl Chloride to Epichlorohydrin by a Reversible Supported Catalyst with H2O2 under Solvent-Free Conditions
Jun Li, Gongda Zhao, Shuang Gao, Ying Lv, Jian Li, and Zuwei Xi
Org. Process Res. Dev. 2006, 10 (5),pp 876–880

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http://dx.doi.org/10.1021/op060108k
22) Large-Scale Synthesis of (R)-2-Amino-1-(2-furyl)ethanol via a Chemoenzymatic Approach
Thomas Purkarthofer, Thomas Pabst, Cor van den Broek, Herfried Griengl, Oliver Maurer, and Wolfgang Skranc
Org. Process Res. Dev. 2006, 10 (3),pp 876–880pp 618–621
Publication Date (Web): March 30, 2006 (Article)

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http://dx.doi.org/10.1021/op050264b
23) Development of a Pilot-Scale Preparation of N-[[(5S)-3-[4-(1,1-Dioxido-4- thiomorpholinyl)-3,5-difluorophenyl]-2-oxo-5-oxazolidinyl]methyl]acetamide, PNU-288034, an Oxazolidinone Antibacterial Agent
Cuong V. Lu, Jiong J. Chen, William R. Perrault, Brian G. Conway, Mark T. Maloney, and Ying Wang
Org. Process Res. Dev. 2006, 10 (2),pp 272–277

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http://dx.doi.org/10.1021/op050207i
24) One-Pot Multistep Synthetic Strategies for the Production of Fenpropimorph Using an Ionic Liquid Solvent
Stewart A. Forsyth, H. Q. Nimal Gunaratne, Christopher Hardacre, Angela McKeown, and David W. Rooney
Org. Process Res. Dev. 2006, 10 (1),pp 94–102

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http://dx.doi.org/10.1021/op050172m
25) Understanding the Origin of Unusual Stepwise Hydrogenation Kinetics in the Synthesis of the 3-(4-Fluorophenyl)morpholine Moiety of NK1 Receptor Antagonist Aprepitant
Karel M. J. Brands, Shane W. Krska, Thorsten Rosner, Karen M. Conrad, Edward G. Corley, Mahmoud Kaba, Robert D. Larsen, Robert A. Reamer, Yongkui Sun, and Fuh-Rong Tsay
Org. Process Res. Dev. 2006, 10 (1),pp 109–117

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http://dx.doi.org/10.1021/op0501895
26) Scaleable Syntheses of Isomeric Limonene Aziridines from the Commercially Available Mixture of cis- and trans-Limonene Oxides
Michael V. Voronkov, Alexander V. Gontcharov, Ramanaiah C. Kanamarlapudi, Paul F. Richardson, and Zhi-Min Wang
Org. Process Res. Dev. 2005, 9 (2),pp 221–224

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http://dx.doi.org/10.1021/op0498464
Спасибо
Последний раз редактировалось Liverpool Чт июл 08, 2010 10:45 am, всего редактировалось 1 раз.
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Shadin
Сообщения: 490
Зарегистрирован: Вт фев 05, 2008 3:16 pm

Re: Org. Process Res. Dev

Сообщение Shadin » Чт июл 08, 2010 9:21 am

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Shadin
Сообщения: 490
Зарегистрирован: Вт фев 05, 2008 3:16 pm

Re: Org. Process Res. Dev

Сообщение Shadin » Чт июл 08, 2010 9:30 am

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