+++J. Med. Chem.

[Liverpool]

Помогите, пожалуйста, со статьями:

1) Synthesis and Characterization of in Vitro and in Vivo Profiles of Hydroxybupropion Analogues: Aids to Smoking Cessation
Ronald J. Lukas, Ana Z. Muresan, M. Imad Damaj, Bruce E. Blough, Xiaodong Huang, Hernn A. Navarro, S. Wayne Mascarella, J. Brek Eaton, Syndia K. Marxer-Miller and F. Ivy Carroll
J. Med. Chem. 2010, 53 (12), pp 4731–4748

Код: Выделить всё

http://dx.doi.org/10.1021/jm1003232

2) Discovery of a Potent, Orally Active 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor for Clinical Study: Identification of (S)-2-((1S,2S,4R)-Bicyclo[2.2.1]heptan-2-ylamino)-5-isopropyl-5-methylthiazol-4(5H)-one (AMG 221)
Murielle M. Vniant, Clarence Hale, Randall W. Hungate, Kyung Gahm, Maurice G. Emery, Janan Jona, Smriti Joseph, Jeffrey Adams, Andrew Hague, George Moniz, Jiandong Zhang, Michael D. Bartberger, Vivian Li, Rashid Syed, Steven Jordan, Rene Komorowski, Michelle M. Chen, Rod Cupples, Ki Won Kim, David J. St. Jean, Jr., Lars Johansson, Martin A. Henriksson, Meredith Williams, Jerk Vallgrda, Christopher Fotsch and Minghan Wang
J. Med. Chem. 2010, 53 (11), pp 4481–4487

Код: Выделить всё

http://dx.doi.org/10.1021/jm100242d

3) Discovery of Novel Selective Norepinephrine Reuptake Inhibitors: 4-[3-Aryl-2,2-dioxido-2,1,3-benzothiadiazol-1(3H)-yl]-1-(methylamino)butan-2-ols (WYE-103231)
David J. O’Neill, Adedayo Adedoyin, Peter D. Alfinito, Jenifer A. Bray, Scott Cosmi, Darlene C. Deecher, Andrew Fensome, Jim Harrison, Liza Leventhal, Charles Mann, Casey C. McComas, Nicole R. Sullivan, Taylor B. Spangler, Albert J. Uveges, Eugene J. Trybulski, Garth T. Whiteside and Puwen Zhang
J. Med. Chem. 2010, 53 (11), pp 4511–4521

Код: Выделить всё

http://dx.doi.org/10.1021/jm100053t

4) Synthesis and Structure−Activity Relationships of Long-acting β2 Adrenergic Receptor Agonists Incorporating Metabolic Inactivation: An Antedrug Approach
Panayiotis A. Procopiou, Victoria J. Barrett, Nicola J. Bevan, Keith Biggadike, Philip C. Box, Peter R. Butchers, Diane M. Coe, Richard Conroy, Amanda Emmons, Alison J. Ford, Duncan S. Holmes, Helen Horsley, Fern Kerr, Anne-Marie Li-Kwai-Cheung, Brian E. Looker, Inderjit S. Mann, Iain M. McLay, Valerie S. Morrison, Peter J. Mutch, Claire E. Smith and Paula Tomlin
J. Med. Chem. 2010, 53 (11), pp 4522–4530

Код: Выделить всё

http://dx.doi.org/10.1021/jm100326d

5) The Identification of Indacaterol as an Ultralong-Acting Inhaled β2-Adrenoceptor Agonist
Franois Baur, David Beattie, David Beer, David Bentley, Michelle Bradley, Ian Bruce, Steven J. Charlton, Bernard Cuenoud, Roland Ernst, Robin A. Fairhurst, Bernard Faller, David Farr, Thomas Keller, John R. Fozard, Joe Fullerton, Sheila Garman, Julia Hatto, Claire Hayden, Handan He, Colin Howes, Diana Janus, Zhengjin Jiang, Christine Lewis, Frederique Loeuillet-Ritzler, Heinz Moser, John Reilly, Alan Steward, David Sykes, Lauren Tedaldi, Alexandre Trifilieff, Morris Tweed, Simon Watson, Elke Wissler and Daniel Wyss
J. Med. Chem. 2010, 53 (9), pp 3675–3684

Код: Выделить всё

http://dx.doi.org/10.1021/jm100068m

6) Identification of Hits as Matrix-2 Protein Inhibitors through the Focused Screening of a Small Primary Amine Library
Wenhui Hu, Shaogao Zeng, Chufang Li, Yanling Jie, Zhiyuan Li and Ling Chen
J. Med. Chem. 2010, 53 (9), pp 3831–3834

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http://dx.doi.org/10.1021/jm901664a

7) 1-(Indolin-1-yl)-1-phenyl-3-propan-2-olamines as Potent and Selective Norepinephrine Reuptake Inhibitors
An T. Vu, Stephen T. Cohn, Puwen Zhang, Callain Y. Kim, Paige E. Mahaney, Jenifer A. Bray, Grace H. Johnston, Elizabeth J. Koury, Scott A. Cosmi, Darlene C. Deecher, Valerie A. Smith, James E. Harrison, Liza Leventhal, Garth T. Whiteside, Jeffrey D. Kennedy and Eugene J. Trybulski
J. Med. Chem. 2010, 53 (5), pp 2051–2062

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http://dx.doi.org/10.1021/jm901559e

8 ) Synthesis of New Thienyl Ring Containing HIV-1 Protease Inhibitors: Promising Preliminary Pharmacological Evaluation against Recombinant HIV-1 Proteases
Carlo Bonini, Lucia Chiummiento, Margherita De Bonis, Nadia Di Blasio, Maria Funicello, Paolo Lupattelli, Rocco Pandolfo, Francesco Tramutola and Federico Berti
J. Med. Chem. 2010, 53 (4), pp 1451–1457

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http://dx.doi.org/10.1021/jm900846f

9) (3R,5S,7as)-(3,5-Bis(4-fluorophenyl)tetrahydro-1H-oxazolo[3,4-c]oxazol-7a-yl)methanol, a Novel Neuroprotective Agent
Kelly E. Desino, Sabah Ansar, Gunda I. Georg, Richard H. Himes, Mary Lou Michaelis, Douglas R. Powell, Emily A. Reiff, Hanumaiah Telikepalli and Kenneth L. Audus
J. Med. Chem. 2009, 52 (23), pp 7537–7543

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http://dx.doi.org/10.1021/jm900254k

10) Discovery and Preclinical Evaluation of [4-[[1-(3-fluorophenyl)methyl]-1H-indazol-5-ylamino]-5-methylpyrrolo[2,1-f][1,2,4]triazin-6-yl]carbamic Acid, (3S)-3-Morpholinylmethyl Ester (BMS-599626), a Selective and Orally Efficacious Inhibitor of Human Epidermal Growth Factor Receptor 1 and 2 Kinases
Ashvinikumar V. Gavai, Brian E. Fink, David J. Fairfax, Gregory S. Martin, Lana M. Rossiter, Christian L. Holst, Soong-Hoon Kim, Kenneth J. Leavitt, Harold Mastalerz, Wen-Ching Han, Derek Norris, Bindu Goyal, Shankar Swaminathan, Bharat Patel, Arvind Mathur, Dolatrai M. Vyas, John S. Tokarski, Chiang Yu, Simone Oppenheimer, Hongjian Zhang, Punit Marathe, Joseph Fargnoli, Francis Y. Lee, Tai W. Wong and Gregory D. Vite
J. Med. Chem. 2009, 52 (21), pp 6527–6530

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http://dx.doi.org/10.1021/jm9010065

11) Antagonists of the Calcium Receptor. 2. Amino Alcohol-Based Parathyroid Hormone Secretagogues
Robert W. Marquis, Amparo M. Lago, James F. Callahan, Attiq Rahman, Xiaoyang Dong, George B. Stroup, Sandra Hoffman, Maxine Gowen, Eric G. DelMar, Bradford C. Van Wagenen, Sarah Logan, Scott Shimizu, John Fox, Edward F. Nemeth, Theresa Roethke, Brian R. Smith, Keith W. Ward and Pradip Bhatnagar
J. Med. Chem. 2009, 52 (21), pp 6599–6605

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http://dx.doi.org/10.1021/jm900563e

12) 1- or 3-(3-Amino-2-hydroxy-1-phenyl propyl)-1,3-dihydro-2H-benzimidazol-2-ones: Potent, Selective, and Orally Efficacious Norepinephrine Reuptake Inhibitors
Puwen Zhang, Eugene A. Terefenko, Jenifer Bray, Darlene Deecher, Andrew Fensome, Jim Harrison, Callain Kim, Elizabeth Koury, Lilly Mark, Casey C. McComas, Cheryl A. Mugford, Eugene J. Trybulski, An T. Vu, Garth T. Whiteside and Paige E. Mahaney
J. Med. Chem. 2009, 52 (18), pp 5703–5711

Код: Выделить всё

http://dx.doi.org/10.1021/jm900888c

Спасибо!!!

[SergSam]