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Synthesis and Structure−Affinity Relationship Investigations of 5-Heteroaryl-Substituted Analogues of the Antipsychotic Sertindole. A New Class of Highly Selective α1 Adrenoceptor Antagonists
Thomas Balle, Jens Perregaard, Martha Teresa Ramirez, Anna Kirstine Larsen, Karina Krøjer Søby, Tommy Liljefors, and Kim Andersen
J. Med. Chem., 2003, 46 (2), pp 265–283
Publication Date (Web): December 11, 2002 (Article)

DOI:

http://dx.doi.org/10.1021/jm020938y

Structure−Activity Relationships of the Cycloalkanol Ethylamine Scaffold: Discovery of Selective Norepinephrine Reuptake Inhibitors
Paige E. Mahaney, Lori K. Gavrin, Eugene J. Trybulski, Gary P. Stack, An T. Vu, Stephen T. Cohn, Fei Ye, Justin K. Belardi, Arthur A. Santilli, Joseph P. Sabatucci, Jennifer Leiter, Grace H. Johnston, Jenifer A. Bray, Kevin D. Burroughs, Scott A. Cosmi, Liza Leventhal, Elizabeth J. Koury, Yingru Zhang, Cheryl A. Mugford, Douglas M. Ho, Sharon J. Rosenzweig-Lipson, Brian Platt, Valerie A. Smith and Darlene C. Deecher
J. Med. Chem., 2008, 51 (13), pp 4038–4049
Publication Date (Web): June 17, 2008 (Article)

DOI:

http://dx.doi.org/10.1021/jm8002262

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