1. Inhibition of Sphingosine 1-Phosphate Lyase for the Treatment of Rheumatoid Arthritis: Discovery of (E)-1-(4-((1R,2S,3R)-1,2,3,4-Tetrahydroxybutyl)-1H-imidazol-2-yl)ethanone Oxime (LX2931) and (1R,2S,3R)-1-(2-(Isoxazol-3-yl)-1H-imidazol-4-yl)butane-1,2,3,4-tetraol (LX2932).
Jeffrey T. Bagdanoff, Michael S. Donoviel.
J. Med. Chem., Article ASAP
- DOI:
http://dx.doi.org/10.1021/jm101183p
Stephan Schann, Stanislas Mayer.
J. Med. Chem. Article ASAP.
- DOI:
http://dx.doi.org/10.1021/jm101069m