1. C–H Functionalization: A New Strategy for the Synthesis of Biologically Active Natural Products
Janine Cossy, Stellios Arseniyadis Sophie Rousseaux, Benoît Liégault, Keith Fagnou
Modern Tools for the Synthesis of Complex Bioactive Molecules
- DOI:
http://dx.doi.org/[doi]10.1002/9781118342886.ch1
Wiley
Keywords:
C–H functionalization, biologically active natural products;transition metal-catalyzed transformations, at C–H bonds;carbon–carbon and carbon–heteroatom bonds;mechanism of C–H bond cleavage in processes
Summary
This chapter contains sections titled
Introduction
Palladium(0)-Catalyzed Intramolecular Direct Arylation
Palladium(0)-Catalyzed Intramolecular Alkenylation of sp2 C-H Bonds
Palladium(0)-Catalyzed Intramolecular Arylation of sp3 C-H Bonds
Palladium(Ii)-Mediated Intramolecular Oxidative Alkenylation of sp2 C-H Bonds
Directing Group-Assisted Palladium(II)-Enabled Carbon-Carbon Bond Formation at sp3 C-H Bonds
Platinum(Ii)-Mediated Alkane Dehydrogenation
Palladium(Ii)-Enabled Carbon-Oxygen Bond Formation at sp3 C-H Bonds
Iridium-Catalyzed Borylation of sp2 C-H Bonds
Rhodium(I)-Catalyzed Intramolecular Directed Alkylation of sp2 C-H Bonds
Rhodium(III)-Catalyzed Synthesis of Nitrogen-Containing Heterocycles
Conclusion
References
