+++Chem Abstract

[Vadim]

Привет! Помогите, пожалуйста, ознакомится с абстрактами статей:

1)Chem.Abstr. 1969 , vol. 70, # 77992c
2)Chem.Abstr. 1969 , vol. 70, # 28933a

[suprachemister]

3-(Substituted phenoxy)pyridazines
By Tamura, Saburo; Kijima, Teruomi
From Jpn. Tokkyo Koho (1968), JP 43011901 B 19680520. Language: Japanese
Manuf. of the title compds. useful as herbicides, sedatives, and analgesics by the reaction of 3-chloropyridazine with substituted phenol is described. Thus, a mixt. of 3 g. 3-chloropyridazine, 3.7 g. m-chloro-p-cresol, and 3.6 g. K2CO3 was heated at 140° for 15 min. and washed with dil. NaOH to give 2.2 g. 3-(3-methyl-4-chlorophenoxy)pyridazine, m. 86° (petroleum ether). Similarly prepd. were 3-[(R-substituted)phenoxy]pyridazines (R and m.p. given): 3-nitro, 86°; 2-Ph, 123-4°; 3-Cl, 90.5°; 4-Cl, 106°; 2,4-Cl2, 98°; 2,6-Cl2, 87-8°; 4-MeO, 88.5°; 4-nitro, 151°.

3-(Substituted phenoxy)pyridazines
By Tamura, Saburo; Kijima, Teruomi
From Jpn. Tokkyo Koho (1968), JP 43011900 B4 19680520. Language: Japanese
Manuf. of I, useful as herbicides, growth-controlling agents for plants, analgesics, and sedatives, is described. In an example, 2 g. 3-(3-chlorophenoxy)-6-chloropyridazine in 50 ml. MeOH is subjected to catalytic redn. using 1 g. 5% Pd-C and 4 ml. concd. NH4OH at 25° under ordinal pressure to give 1 g. I (X = 3-Cl), m. 90.5° (ligroine). Similarly prepd. are the following I (X and m.p. given): 2-Cl, 108-9°; 2,6-Cl2, 87-8°; 3-Me, 47°; 3-Me-4-Cl, 86°; 2-Ph, 123-4°; 4-Cl, 106°; 2,4-Cl2, 98°; 4-OMe, 88.5°; 2-Me, 78-80°; 2,4,6-Cl3, 153°; 2-iso-Pr, 96.5-8°; 2-Pr, 58-61°; 2-tert-Bu, 78-9°.