+++ Спасибо suprachemister

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Ув. Господа посмотрите пож-та синтез, физико-химические сво-ва и биоактивность:

Код: Выделить всё

O=C(O)CCCCCCCC(=O)OCC(O)CO

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References
1. Cleansing and antimicrobial skin care compositions comprising glyceryl esters
By Whewell, Christopher J.
From U.S. Pat. Appl. Publ. (2008), US 20080089854 A1 20080417. Language: English, Database: CAPLUS
Provided are compns. which are suitable for topical application to human skin for cleansing and anti-microbial properties. In one preferred embodiment, the compns. include a glyceryl monoazelate ester. In another embodiment, the compns. include a glyceryl monoazelate monolaurate ester. It is postulated that bacteria on the skin cleave the ester linkage of a compd. according to the disclosure that is applied to the skin, which causes liberation of the acid moiety from the ester, which acid moiety then inhibits or kills the bacterium. Compns. according to the disclosure may comprise skin cre...

2. Personal care compositions comprising glyceryl esters
By Whewell, Christopher J.
From U.S. (2007), US 7300957 B1 20071127. Language: English, Database: CAPLUS
Compns. suitable for topical application to human skin and hair for cleansing and antimicrobial properties comprising glycerol esters are provided. In one preferred embodiment, the compns. include a glyceryl monoazelate ester. In another embodiment, the compns. include a glyceryl monoazelate monolaurate ester. It is postulated that bacteria on the skin cleave the ester linkage of a compd. according to the invention that is applied to the skin, which causes release of the acid moiety from the ester, which acid moiety then inhibits or kills the bacterium. Compns. according to the invention m...

3. Dicarboxylic acid esters a dermatological agents
By Shiga, Takuo; Nabeta, Kazuo; Nakano, Hiroyuki; Suzuki, Toshimitsu
From U.S. (1987), US 4661519 A 19870428. Language: English, Database: CAPLUS
Title compds. R1O2C(CH2)nCO2R2 (I: n = 5-11; R1 = glyceryl, R2 = H, glyceryl) in pharmaceutically acceptable carriers are used as dermatol. applications for reducing pigmentation of freckles, acne and liver spots. Esterification of azelaic acid with glycerin gave the mono- or diglyceryl azelates (depending on stoichiometry) which were tested and judged superior to conventional products in half-face comparison tests against liver spots, freckles and acne. A skin cream was formulated contg. diglyceryl azelate 10, cetanol 3.0, spermaceti 4.0, stearic acid 1.0, squalene 7.0, sorbitan monooleate ...

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