Chemistry of amino acids & peptides (books)

[Peprosyn]

Thanks for sharing! Please upload other volumes (V33,V34 and V35)! Thanks!

[Upstream]

Peprosyn: Glad to hear that someone else needs these books too! Sorry for the delay. Vol.35 is under construction.

Amino Acids, Peptides and Proteins. Vol.34. A Review of the Literature Published during 2001 (Specialist Periodical Reports).
Senior Reporters: G.C. Barrett & J. S. Davies; Royal Society of Chemistry, 2003, 329 pp.

Код: Выделить всё

http://narod.ru/disk/6882356000/v34_01_03.rar.html

Amino Acids, Peptides and Proteins Vol.33. A Review of the Literature Published during 2000 (Specialist Periodical Reports).
Senior Reporters: G.C. Barrett & J. S. Davies; Royal Society of Chemistry, 2002, 443 pp.

Код: Выделить всё

http://narod.ru/disk/6882099000/v33_00_02.rar.html

Mirrows are always encouraged!
На всякий случай продублирую здесь ссылки на мои прошлогодние заливки, у которых на днях истекает срок:
Гринштейн Дж., Виниц М. Химия аминокислот и пептидов. Перевод с английского. М., Мир, 1965, 821 с.
Нестареющее практическое руководство, переполненное проверенными методиками и точной справочной информацией. Образец для подражания, не уступающий Губен-Вейлю и Organic Synthesis. Непременно загляните в приложение, где приведена чумовая таблица с условиями кристаллизации аминокислот. Жаль, что никто не следует этому примеру. И мы с вами в том числе.

Код: Выделить всё

http://narod.ru/disk/4187527000/Greenstein_russ.rar.html 
In Russian!

Amino Acids: A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References. (J.N. Parker and P.M. Parker, eds) 2003, ICON Group International: San Diego; 400+pp.
Не без удивления обнаружил, что интернет ресурсов по теме на порядок больше, чем я полагал. Особую ценность представляет для биохимиков и биомедиков.

Код: Выделить всё

http://narod.ru/disk/5272518000/AAs.rar.html

[Peprosyn]

Спасибо за обмен! Upstream, Я люблю тебя очень и даст вам большой поцелуй со всем моим сердцем.

[Upstream]

Так, похоже у моего любознательного коллеги из Китая появился знакомый русский, любезно подсобивший ему с этой "валентинкой"...
Dear Peprosyn:
You're wellcome!
Personally, I've got the actual meaning behind your first public exercise in Russian, but all my Russian colleagues here clearly were having a lot of fun while reading your post. Nothing indesent, but it sounds like a passionate Valentine greetings sent to someone you love... I guess some kind of joker helped you to compose it. Don't take this serious, but beware writing in Russian to someone whose sense of humour you're not sure of.
Best regards. =Upstream=

[Cherep]

It might have been some sort of screwed up (in its design) translating software also.

[FOX-7]

Upstream! Спасибо! Ждем продолжения темы.

[Upstream]

Synthetic Peptides: A User's Guide (Advances in Molecular Biology). Gregory Grant, ed., Oxford University Press, USA, 2002, 400 pp.

Код: Выделить всё

http://narod.ru/disk/7378118000/SyntheticPeptidesGrant02.rar.html

The first synthetic peptides were produced a century ago. In the ensuing period, they have developed as valuable research tools that are readily available to all researchers. However, since most researchers do not make their own peptides, they are often unfamiliar with not only the synthetic chemistry but also with important and useful aspects of design, analysis, handling, and applications. This volume is the second edition of a volume that was first published 10 years ago. It is written by experts in the field who provide detailed descriptions as well as practical advice advice for producing and using synthetic peptides. The various chapters cover peptide design considerations, the synthetic chemistry, the evaluation of the synthetic product, and the modern applications of synthetic peptides. This includes the basic principles of peptide structure, analysis and chain assembly as well as the latest in selective disulfide bond formation, new strategies for the production of large peptides, and sequencing peptides by mass spectrometry. This book was designed with the intent of providing useful information both for the novices to the field as well as more seasoned practitioners. Its contents will help prevent problems commonly encountered and allow scientists to optimize their use of synthetic peptides.
BooknewsDetailed descriptions of processes involved in producing and using synthetic peptides are provided here. Information is given on peptide design considerations, synthetic chemistry, evaluation of the synthetic product, and modern applications of synthetic peptides. Basic principles of peptide structure, analysis, and chain assembly are reviewed, and innovations such as sequencing peptides by mass spectrometry are discussed. This second edition reflects changes in the field over the past 10 years.

Основной химический раздел написан под присмотром Джорджа Barany, одного из наиболее продвинутых и последовательных учеников Merrifield-a. Это вселяет надежду, что там не так много ошибок и неточностей, тем более, что это второе издание.

До кучи переношу сюда из старой мелкой темки ссылку, срок которой истекает. Вдруг кому-то ещё пригодится:
Остерман Л.А. Хроматография белков и нуклеиновых кислот. (1985)
ВЭЖХ в биохимии /под ред. А. Хеншен, К.-П. Хупе. (1988)
Dechow F.J. Separation and Purification Techniques in Biotechnology. (1989)
Guide to Protein Purification. Meth. Enzymol. v182 (1990)
Practical Protein Chromatography. MMBv11 (1992)
Peptide Analysis Protocols. MMBv36 (1992)
Protein and Peptide Analysis by Mass Spectroscopy. MMBv61 (1996)
Protein Purification Protocols. MMBv244 (2004)
HPLC of Peptides and Proteins. MMBv251 (2004)
(MMB=Methods in Molecular Biology)

Код: Выделить всё

http://narod.ru/disk/4400755000/Cromatogr.rar.html

[Peprosyn]

Upstream! the downstream process books on peptide & protein are really good! Excellent job!

[Upstream]

Начинаю обнародование подборки, любезно предоставленной коллегой Peprosyn.
Во-первых, у него оказался pdf-оригинал книги, которую я прежде выкладывал в виде очень непрофессионального скана (соответствующая тема удалена):
Fmoc solid phase peptide synthesis: A practical approach. W.C. Chan and P.D. White, Eds. Oxford University Press, NY, 2000

Код: Выделить всё

http://narod.ru/disk/7768139000/01-Fmoc%20Solid%20Phase%20Peptide%20Synthesis.pdf.html

Kindly provided by colleague Peprosyn

[Upstream]

Усилиями коллеги Peprosyn удалось раздобыть тома 35 и 17-20 Specialist Periodical Reports:
Amino Acids, Peptides and Proteins. Vol.35. A review of the literature published during 2002. Davies J.S. (Editor), Royal Society of Chemistry, 2006.

Код: Выделить всё

http://narod.ru/disk/7731140000/Amino%20Acids%2C%20Peptides%20and%20Proteins%20Volume%2035.pdf.html
Uploaded by Peprosyn

Amino Acids and Peptides. Vols. 17-20. A review of the literature published during 1984-87. Jones, J.H., (Senior reporter), RSC, 1986-89.

Код: Выделить всё

http://narod.ru/disk/7730898000/Amino%20Acids%20and%20Peptides%20Volume%2020.pdf.html
http://narod.ru/disk/7729967000/Amino%20Acids%20and%20Peptides%20Volume%2019.pdf.html
http://narod.ru/disk/7728976000/Amino%20Acids%20and%20Peptides%20Volume%2018.pdf.html
http://narod.ru/disk/7727342000/Amino%20Acids%20and%20Peptides%20Volume%2017.pdf.html
Uploaded by Peprosyn

[Peprosyn]

The series by RCS are very good gifts to peptide and amino acid chemists.

[bromin]

Коллеги, попала в руки бумажная книга Методы химии белков (Дж. Бейли) перевод с анг. Мир, Москва 1965.
Отсканировал содержание, если кого заинтересует отсканирую всю

[Upstream]

2Bromin:
Думаю, не стоит в эту книгу инвестировать усилия: уж больно резко эта область продвинулась с тех пор. Не эту тему десятки современных изданий расшарены.
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Продолжим наши игры?

Advances in Amino Acid Mimetics and Peptidomimetics, A. Abell, Ed., JAI Press,
Vol.1, 1997, 302 pp.

Код: Выделить всё

http://ifile.it/0cdx1tg/0762302003.zip
http://www.filefactory.com/file/0d6478/n/0762302003_zip 

Vol.2, 1999, 316 pp.

Код: Выделить всё

http://ifile.it/386g7t9/0762306149.zip
http://www.filefactory.com/file/ce5cbc/n/0762306149_zip 

Peptidomimetics are compounds which mimic the biological activity of peptides while offering the advantages of increased bioavailability, biostability, bioefficiency, and bioselectivity against the natural biological target of the parent peptide. Examples of peptidomimetics have been isolated as natural products, synthesized as libraries from novel subunits, and designed on the basis of X-ray crystallographic studies and through an intricate knowledge of the biological mode of action of natural peptides. They offer challenging synthetic targets and are increasingly important medicinal agents and biological probes. As a consequence, peptidomimetics embrace much of what is modern medicinal and organic chemistry. This volume highlights some recent and exciting developments in the area.

This book presents a new domain, whose applications might be greatly increased in the coming years. Construction of peptidomimetic molecules it a useful tool for the development of new drugs. The major drawback of peptides as possible drugs is their poor bioavailability and their degradation in the body. Therefore, molecules resembling the tertiary structures of interesting peptides, but having more suitable bioavailability properties might proove very useful as candidate drugs. That is why this discipline is very promising. To date, i haven’t found any text books addressing this issue, this book might be the first one. I liked the fact that its contents cover many medical domains. However, I would have liked that the authors have addressed the problem of increasing bacterial resistance, the need to develop new antibacterials, and eventually the possible role of peptidomimetics in that field. Another thing that i would have liked to find in the contents, is a brief review on the phage display technique, its potential of finding useful peptides that might serve for the construction of peptidomimetics.

Peptidomimetics have found wide application as bioavailable, and often potent mimetics of natural peptides. They form the basis of important classes of enzyme inhibitors, they act as receptor agonists and antagonists, and they have even been used to mimic DNA structure. Recent advances in the use of solid-phase organic synthesis have paved the way for the preparation of libraries of these structures to allow the rapid optimization of theri biological properties and hence therapeutic potential. We are also beginning to gain a greater understanding of the structural features of this class of compounds that influence their ability to permeate membranes, and their rate of clearance and metabolism. This volume brings together many of these critical issues by highlighting recent advances in a number of core peptidomimetic-based research.

Код: Выделить всё

Origin: http://www.addebook.com

[bromin]

2Bromin:
Думаю, не стоит в эту книгу инвестировать усилия: уж больно резко эта область продвинулась с тех пор. Не эту тему десятки современных изданий расшарены.

Спасибо коллега, что сказали свое мнение Не буду сканировать пока

[Ося]

Нашёл на гигапедии (вроде здесь не было)
Peptidomimetics Protocols (Methods in Molecular Medicine), 1999-01
автор(ы): Wieslaw M. Kazmierski (Editor)

Код: Выделить всё

http://ifile.it/gv2ctp6/38177___023-peptidomimetics_protocols.pdf

[Upstream]

Пара исторических обзоров по синтезу пептидов в растворе, которые не утратили актуальности благодаря своей обстоятельности и вкраплениям проверенных методик:
Katchalski, E., Sela, M. Synthesis and chemical properties of poly-alpha-amino acids. Adv.Protein Chem.1958, 13:243-492.

Код: Выделить всё

http://narod.ru/disk/7800529000/37-Synthesis%20and%20Chemical%20Properties%20of%20Ploy-%CE%B1-Amino%20Acids.pdf.html

Katsoyannis, P.G., Schwartz, G.P. The synthesis of peptides by homogeneous solution procedures. Methods Enzymol.,1977, v.47, pp.501-78.

Код: Выделить всё

http://narod.ru/disk/7799738000/39-The%20Synthesis%20of%20Peptides%20by%20Homogeneous%20Solution%20Procedures.pdf.html

Credits to Peprosyn who uploaded the above.=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=x=

M. H. V. Van Regenmortel, J. P. Briand, S. Muller, S. Plaue. Synthetic Polypeptides as Antigens. (Laboratory Techniques in Biochem. Mol. Biology, v.19). Elsevier Sci. Pub. Co. 1988, 350 pp.
Synthetic Polypeptides as Antigens is the first volume to give a comprehensive treatment under one cover of the various techniques used for synthesizing peptides by the solid phase approach, for coupling them to carrier molecules and analyzing their immunochemical activity by a variety of immunoassays. This book also describes methods for analyzing the antigenic structure of proteins and predicting the location of their antigenic sites. Recent advances in the detection of gene products with antipeptide antibodies, and the still controversial use of synthetic peptides as vaccines are also described. The book provides: - detailed descriptions of procedures - extensive bibliography - detailed analysis of the structural basis of antigenicity in proteins and is intended for researchers and graduate students in molecular biology, protein structure, immunology, virology.

Код: Выделить всё

 http://ifile.it/dweg4qo/0444809759.rar
Found on http://www.addebook.com/tech2/category/chemistry 

[Upstream]

На всякий случай обнародываю "горящие" ссылки на статьи, которые комрад Peprosyn выложил по своей инициативе + пару моих заливок "по требованию":

Waleed Danho (Hoffmann-La Roche Inc. Nutley, NJ 07110, USA). Opportunities and Challenges of Developing Peptide Drugs in the Pharmaceutical Industry (35 slides). Presentation at the TIDES Conference, May 18-21, 2008 Las Vegas, NV.

Код: Выделить всё

http://narod.ru/disk/7799933000/TIDES-2008(2).pdf.html

Seebach D., Kimmerlin T., Sebesta R., Campo M.A., Beck A.K. How we drifted into peptide chemistry and where we have arrived at. Tetrahedron 2004, 60, 7455-7506.

Код: Выделить всё

http://narod.ru/disk/7800215000/How%20we%20drifted%20into%20peptide%20chemistry%20and%20where%20we%20have%20arrived%20at.pdf.html

Mueller-Hartwieg C.D., Akyel, K.G., and Zimmermann, J. Synthesis and conformational investigation of cyclic dipeptides: 7-membered rings containing alpha- and beta-amino acids. J.Peptide Sci. 2003, 9(3), 187-199.

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http://narod.ru/disk/7800106000/Solution%20versus%20solid-phase%20cyclization%20strategies%20for%20large%20sidechain%20lactam-bridged%20peptides_A%20comparative%20study.pdf.html

Sheng Jiang, Zheng Li, Ke Ding and Peter P. Roller. Recent Progress of Synthetic Studies to Peptide and Peptidomimetic Cyclization. Curr. Org. Chem. 2008, 12, 1502-1542.

Код: Выделить всё

http://narod.ru/disk/7800070000/Recent%20Progress%20of%20Synthetic%20Studies%20to%20Peptide%20and%20Peptidomimetic%20Cyclization.pdf.html

Uploaded by Peprosyn
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Najera, C. and Yus, M. Pyroglutamic acid: a versatile building block in asymmetric synthesis. Tetrahedron: Asymmetry 1999, 10, 2245-2303.

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http://narod.ru/disk/8541574000/PyrReview.zip.html

Gerd Hummel, Ulrich Reineke and Ulf Reimer. Translating Peptides into Small Molecules. Mol.BioSyst. 2006, 2, 499-508.

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http://www.rsc.org/delivery/_ArticleLinking/DisplayArticleForFree.cfm?doi=b611791k&JournalCode=MB

Collection of 20 papers and newsletters on PEGs with reactive end groups and PEG-ilation methods (13 Mb):

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http://narod.ru/disk/7830097000/PEG-related.rar.html

[horks]

Спасибо, коллега!

[Upstream]

Non-Natural Amino Acids (Tom W. Muir, John N. Abelson, Eds.), Methods in Enzymology 2009, Vol.462, Academic Press, pp.318
3,53 MB

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http://rapidshare.com/files/262302871/0123743109.rar 

На самом деле этот том посвящён native chemical ligation & other semisynthetic approaches to proteins, как видно из оглавления:

1. Protein Phosphorylation by Semisynthesis: From Paper to Practice
2. Protein Engineering with the Traceless Staudinger Ligation
3. Replacement of Y730 and Y731 in the a2 Subunit of Escherichia coli Ribonucleotide Reductase with 3-Aminotyrosine using an Evolved Suppressor tRNA/tRNA-Synthetase Pair
4. Semisynthesis of Proteins Using Split Inteins
5. Expressed Protein Ligation for Metalloprotein Design and Engineering
6. Using Expressed Protein Ligation to Probe the Substrate Specificity of Lantibiotic Synthetases
7. Semisynthesis of Kþ Channels
8. Segmental Isotopic Labeling of Proteins for Nuclear Magnetic Resonance
9. Semisynthesis of Membrane-Attached Prion Proteins
10. Use of Intein-Mediated Protein Ligation Strategies for the Fabrication of Functional Protein Arrays
11. Semisynthesis of Ubiquitylated Proteins

[LEDI]

Thank you, Upstream!