+++13 статей из разных издательств

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1.Solubility of sparingly-soluble ionizable drugs
Advanced Drug Delivery Reviews, Volume 59, Issue 7, 30 July 2007, Pages 568-590
Alex Avdeef

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http://dx.doi.org/10.1016/j.addr.2007.05.008

2.Hydrogen Bonding and Basicity of Cyclic Imines
Scott Searles, Milton Tamres, Frank Block, Lloyd A. Quarterman
J. Am. Chem. Soc., 1956, 78 (19), pp 4917–4920

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http://dx.doi.org/10.1021/ja01600a029

3.Molecular determinants of recognition and activation at the cerebellar benzodiazepine receptor site Laura T. Schove, Juan J. Perez and Gilda H. Loew
Bioorganic & Medicinal Chemistry Volume 2, Issue 10, October 1994, Pages 1029-1049

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http://dx.doi.org/10.1016/S0968-0896(00)82053-2

4.Design, synthesis, and binding affinities of potential positron emission tomography (PET) ligands with optimal lipophilicity for brain imaging of the dopamine D3 receptor. Part II
Bioorganic & Medicinal Chemistry, Volume 17, Issue 2, 15 January 2009, Pages 758-766
Marcello Leopoldo, Enza Lacivita, Paola De Giorgio, Marialessandra Contino, Francesco Berardi and Roberto Perron

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http://dx.doi.org/10.1016/j.bmc.2008.11.044

5.Structural Modifications of N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-Aryl-1-piperazinehexanamides: Influence on Lipophilicity and 5-HT7 Receptor Activity. Part III
Marcello Leopoldo, Enza Lacivita, Paola De Giorgio, Claudia Fracasso
J. Med. Chem., 2008, 51 (18), pp 5813–5822

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http://dx.doi.org/10.1021/jm800615e

6.Structure−Activity Relationship Study on N-(1,2,3,4-Tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides, a Class of 5-HT7 Receptor Agents.
Marcello Leopoldo, Enza Lacivita, Marialessandra Contino, Nicola A. Colabufo
J. Med. Chem., 2007, 50 (17), pp 4214–4221

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http://dx.doi.org/10.1021/jm070487n

7.Synthesis and binding profile of constrained analogues of N-[4-(4-arylpiperazin-1-yl)butyl]-3-methoxybenzamides, a class of potent dopamine D3 receptor ligands
Leopoldo, Marcello; Lacivita, Enza; Colabufo, Nicola A.; Berardi, Francesco; Perrone, Roberto
Journal of Pharmacy and Pharmacology, Volume 58, Number 2, February 2006 , pp. 209-218(10)

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http://dx.doi.org/10.1211/jpp.58.2.0008

8.First Structure−Activity Relationship Study on Dopamine D3 Receptor Agents with N-[4-(4-Arylpiperazin-1-yl)butyl]arylcarboxamide Structure
Marcello Leopoldo, Enza Lacivita, Nicola A. Colabufo, Marialessandra Contino
J. Med. Chem., 2005, 48 (25), pp 7919–7922

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http://dx.doi.org/10.1021/jm050729o

9.Structure−Affinity Relationship Study on N-[4-(4-Arylpiperazin-1-yl)butyl]arylcarboxamides as Potent and Selective Dopamine D3 Receptor Ligands
Marcello Leopoldo, Francesco Berardi, Nicola A. Colabufo, Paola De Giorgio
J. Med. Chem., 2002, 45 (26), pp 5727–5735

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http://dx.doi.org/10.1021/jm020952a

10.PH-metric log P 11. pKa determination of water-insoluble drugs in organic solvent–water mixtures
Journal of Pharmaceutical and Biomedical Analysis, Volume 20, Issue 4, August 1999, Pages 631-641
A. Avdeef, K. J. Box, J. E. A Comer, M. Gilges, M. Hadley, C. Hibbert, W. Patterson and K. Y. Tam

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http://dx.doi.org/10.1016/S0731-7085(98)00235-0

11.Microscale titrimetric and spectrophotometric methods for determination of ionization constants and partition coefficients of new drug candidates
Michael E. Morgan, Kui Liu, Bradley D. Anderson
Journal of Pharmaceutical Sciences
Volume 87, Issue 2 , Pages238 - 245

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http://dx.doi.org/10.1021/js970057s

12.pH-metric log P. II: Refinement of partition coefficients and lonization constants of multiprotic substances
Alex Avdeef
Journal of Pharmaceutical Sciences
Volume 82, Issue 2 , Pages183 - 190

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http://dx.doi.org/10.1002/jps.2600820214

13.pH-Metric log P. Part 1. Difference Plots for Determining Ion-Pair Octanol-Water Partition Coefficients of Multiprotic Substances
Alex Avdeef
Quantitative Structure-Activity Relationships
Volume 11, Issue 4 , Pages510 - 517

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http://dx.doi.org/10.1002/qsar.2660110408

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