+++Поиск в Reaxys

[urri]

Добрый день!
Посмотрите,пожалуйста,получение

OCc1nccn1C1CC1
OC(=O)c1ccc(s1)-c1ncc[nH]1
CCOC(=O)c1ccc(s1)-c1ncc[nH]1

Спасибо!

[mishka]

есть только получ
1-cyclopropyl-2-imidazolemethanol

из 1-cyclopropylimidazole-2-carboxyaldehyde

Stage #1: 1-cyclopropylimidazole-2-carboxyaldehyde With lithium aluminium tetrahydride In tetrahydrofuran at 0℃;
Stage #2: With sodium hydroxide; water In tetrahydrofuran at 0 - 20℃; for 40h;

Experimental Procedure
Current Patent Assignee: TAKEDA PHARMACEUTICAL - EP1422228, 2004, A1
Location in patent: Page 231

и из
1-cyclopropyl-1H-imidazole + параформальдегид

at 170℃; for 0.666667h;
15.6%
Tasaka; Teranishi; Matsushita; Tamura; Hayashi; Okonogi; Itoh
[Chemical and Pharmaceutical Bulletin, 1994, vol. 42, # 1, p. 85 - 94]

[urri]

Спасибо!