+++ Поиск в Reaxys

[Medz]

Помогите, пожалуйста, найти методики синтеза данного соединения:
2,5-Dimethylimidazole-4-carboxylic acid
84255-24-3
C1(C)=C(C(O)=O)N=C(C)N1

2.png

C1.mol

[mishka]

получение одно (упомянуто в патенте)

Reaction ID: 24985662
в схеме исходное(ые) не показано(ы)
BASF Aktiengesellschaft
US4672128, 1987, A

1 2,5-Dimethylimidazole-4-carboxylic acid
EXAMPLE 1 2,5-Dimethylimidazole-4-carboxylic acid 12 g (0.125 mole) of 2,4-dimethylimidazole, 42.5 g (0.3 mole) of potassium carbonate and 100 ml of liquid carbon dioxide were stirred for 5 hours at 150° C. in an autoclave, the reaction pressure being 130 bar. The reacted mixture was pulverized and suspended in 100 ml of water, and the stirred suspension was brought to pH 5-6 with hydrochloric acid. The precipitate which separated out was filtered off and dried to give 13 g (74% of theory) of pure 2,5-dimethylimidazole-4-carboxylic acid of melting point 234° C. (decomposition).

[Medz]

Большое спасибо !!!