Добрый день)
Возникла необходимость - посмотреть в Реаксисе синтез O=S(=O)(O)c3cc(c1nc2ccccc2s1)c(O)cc3
Благодарю)
Поиск в Reaxys
Re: Поиск в Reaxys
не рисуйте ароматические связи в пятичленном цикле - ничего не находит тогда реаксис (обычные двойные и одинарные надо)
одна ссылка
Barros, Hélio L.; Marques, Sandra M.T.; Stefani, Valter
[Journal of the Brazilian Chemical Society, 2019, vol. 30, # 3, p. 509 - 521]
из 2-amino-benzenethiol + 5-sulfosalicylic Acid
With polyphosphoric acid at 140 - 180℃;
выход 71%
Experimental Procedure
General procedure for the synthesis of the benzazole dyesHB-6, HB-7, HB-9 and HB-11
General procedure: The general methodology for benzazole dye synthesisis presented in Scheme 1. The reaction consists of thecondensation of substituted salicylic acid derivativeswith ortho-substituted anilines in polyphosphoric acidwith the temperature ranging from 140 to 180 °C. Thesecompounds were prepared by the present authors, andthey are in patent pending at the National Instituteof Intellectual Property.38 Some of them have beensuccessfully used to reveal latent fingermarks on thesticky side of different types and colors of adhesive tape1and for the visualization of Oxyuris equi eggs.8 Thesebenzazole dyes are water-soluble and fluorescent in theblue-orange region when exposed to longwave UV light.Figure 3 shows the fluorescent dyes in the solid state underwhite light (Figure 3a) and ultraviolet light of 365 nm(Figure 3b), where we can see an intense fluorescenceemission. Some sulfonated benzothiazole derivatives were patented in 1970 by Freyermuth,39 using differentmethodology to introduce sulfonate group.
одна ссылка
Barros, Hélio L.; Marques, Sandra M.T.; Stefani, Valter
[Journal of the Brazilian Chemical Society, 2019, vol. 30, # 3, p. 509 - 521]
из 2-amino-benzenethiol + 5-sulfosalicylic Acid
With polyphosphoric acid at 140 - 180℃;
выход 71%
Experimental Procedure
General procedure for the synthesis of the benzazole dyesHB-6, HB-7, HB-9 and HB-11
General procedure: The general methodology for benzazole dye synthesisis presented in Scheme 1. The reaction consists of thecondensation of substituted salicylic acid derivativeswith ortho-substituted anilines in polyphosphoric acidwith the temperature ranging from 140 to 180 °C. Thesecompounds were prepared by the present authors, andthey are in patent pending at the National Instituteof Intellectual Property.38 Some of them have beensuccessfully used to reveal latent fingermarks on thesticky side of different types and colors of adhesive tape1and for the visualization of Oxyuris equi eggs.8 Thesebenzazole dyes are water-soluble and fluorescent in theblue-orange region when exposed to longwave UV light.Figure 3 shows the fluorescent dyes in the solid state underwhite light (Figure 3a) and ultraviolet light of 365 nm(Figure 3b), where we can see an intense fluorescenceemission. Some sulfonated benzothiazole derivatives were patented in 1970 by Freyermuth,39 using differentmethodology to introduce sulfonate group.
Re: Поиск в Reaxys
Спасибо) Да, я в структуре пятичленного кольца нарисовал обычную двойную связь, даже не знаю как рисовать ароматическую...
Re: Поиск в Reaxys
связи между атомами, записанными (нарисованными) в смайлсе маленькими латинскими буквами, являются ароматическими.
Надо
Надо
Код: Выделить всё
O=S(C1=CC=C(O)C(C2=NC3=CC=CC=C3S2)=C1)(O)=O
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